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Publications

2001

Grainge I, Lee J, Xu CJ, Jayaram M. (2001). "DNA recombination and RNA cleavage activities of the Flp protein: roles of two histidine residues in the orientation and activation of the nucleophile for strand cleavage." J. Mol. Biol. 314(4):717-33.

Sau AK, DeVue Tribble G, Grainge I, Frohlich RF, Knudsen BR, Jayaram M. (2001). "Biochemical and kinetic analysis of the RNase active sites of the integrase/tyrosine family site-specific DNA recombinases." J. Biol. Chem. 276(49):46612-23.

Lisby M, Olesen JR, Skouboe C, Krogh BO, Straub T, Boege F, Velmurugan S, Martensen PM, Andersen AH, Jayaram M, Westergaard O, Knudsen BR. (2001). "Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation." J. Biol. Chem. 276(23):20220-7.

Frohlich RF, Hansen SG, Lisby M, Grainge I, Westergaard O, Jayaram M, Knudsen BR. (2001). "Inhibition of Flp recombinase by the topoisomerase I-targeting drugs, camptothecin and NSC-314622." J. Biol. Chem. 276(10):6993-7.

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