Stein Lab


Recent Publications

Cho, Y.S., Stevens, L. M., Sieverman, K. J., Nguyen, J., and Stein, D. (2012). A ventrally localized protease in the Drosophila egg controls embryo dorsoventral polarity.  Curr. Biol. 22, 1013-1018.

Stein, D., Charatsi, I., Cho, Y.S., Zhang, Z., Nguyen, J., Delotto, R., Luschnig, S., and Moussian, B. (2010). Localization and activation of the Drosophila protease Easter require the ER-resident Saposin-like  protein Seele. Curr. Biol. 20, 1953-1958.

Cho, Y.S., Stevens, L.M., and Stein, D. (2010). Pipe-dependent ventral processing of Easter by Snake is the defining step in Drosophila embryo DV axis formation. Curr. Biol. 20, 1133-1137.

Zhang, Z., Zhu, X., Stevens, L.M., and Stein, D. (2009). Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe. Development 136, 2779-2789.

Zhang, Z., Stevens, L.M., and Stein, D. (2009). Sulfation of eggshell components by Pipe defines dorsal-ventral polarity in the Drosophila embryo. Curr. Biol. 19, 1200-1205.

Stein, D., and Lasko, P. (2008). The 30th anniversary Crete fly meeting: from individual molecules to 12 genomes, and beyond. Fly 2, 326-333.

Stein, D., Cho, Y. S., Zhang, Z., and Stevens, L. M. (2008).  No requirement for localized Nudel protein expression in Drosophila embryonic axis formation. Fly 2, 220-228.

Zhu, X., Stevens, L. M. and Stein, D. (2007). Synthesis of the sulfate donor PAPS in either the Drosophila germline or somatic follicle cells can support embryonic dorsal-ventral axis formation. Development 134, 1465-1469.

Biswas R., Stein, D., and Stanley, E. R. (2006). Drosophila Dok is required for embryonic dorsal closure. Development 133, 217-227.

Werz, C.,  Lee, T, V., Lee, P. L., Lackey, M., Bolduc, C., Stein, D. S., and Bergmann, A. (2005). Mis-specified cells die by an active gene-directed process, and inhibition of this death results in cell fate transformation in Drosophila. Development 132, 5343-5352.

Zhu, X., Sen, J., Stevens, L., Goltz, J. S., and Stein, D. (2005). Drosophila Pipe protein activity in the ovary and the embryonic salivary gland do not require heparan sulfate glycosaminoglycans. Development 132, 3813-3822.

Zhu, X., and Stein, D. (2004). RNAi-mediated inhibition of gene function in the follicle cell layer of the Drosophila Ovary. Genesis 40, 101-108.

Maines, J., Stevens, L.M., Tong, X., and Stein, D. (2004). Drosophila dMyc is required for ovary cell growth and endoreplication. Development 131, 775-786.            

Lüders, F., Segawa, H., Stein, D., Selva, E.M., Perrimon, N., Turco, S.J.,  and Häcker, U. (2003). slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila EMBO. Journal  22, 3635-3644.

Ten Hagen, K.G., Tran, D.T., Gerken, T.A., Stein, D.S., and Zhang, Z. (2003). Functional characterization and expression analysis of members of the UDP- GalNAc:Polypeptide N-acetylgalactosaminyltransferase family from  Drosophila melanogaster. J. Biol. Chem. 278, 35039-35048.

Stevens, L.M., Beuchle, D., Jurcsak, J., Tong, X., and Stein, D. (2003). The Drosophila embryonic patterning determinant torsolike is a component of the eggshell. Current Biology 13, 1058-1063.

Amiri, A., and Stein, D. (2002). Dorsoventral Patterning: A direct Route from Ovary to Embryo. Current Biology 12, R532-534.

Stein, D., and Stevens, LM. (2001). The torso ligand, unmasked? Sci. STKE 98, pe2.

Fernandez, N.Q., Grosshans, J., Goltz, J.S., and Stein, D.  (2001). Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation. Development 128, 2963-2974.

Sen, J., Goltz, J.S., Konsolaki, M., Schüpbach, G., and Stein, D. (2000). Windbeutel is required for function and subcellular localization of the Drosophila patterning protein Pipe. Development 127, 5541-5550.

Bray, S., and Stein, D. (2000). Developmental biology. Post-expressionist flies. Nature 407, 314-315.

Jordan, K.C., Clegg, N.J., Blasi, J.A., Morimoto, A.M., Sen, J., Stein, D., McNeill, H., Deng, W.-M., Tworoger, M. & Ruohola-Baker, H. (2000). The homeobox gene mirror links EGF signaling to embryonic dorso-ventral axis formation through Notch activation. Nature Genetics 24, 4239-433.

Fernandez, R., Takahashi, F., Liu, Z., Steward, R., Stein, D., and Stanley, E.R. (2000). The Drosophila shark tyrosine kinase is required for embryonic dorsal closure. Genes and Development 14, 604-614.

Han, D. D., Stein, D., and Stevens, L.M.  (2000). Investigating the function of follicular subpopulations during Drosophila oogenesis through hormone-dependent enhancer-targeted cell ablation. Development 127, 573-583.

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The Section of Molecular Cell and Development is one of four units in the School of Biological Sciences. Other Sections are Integrative Biology, Molecular Genetics and Microbiology and Neurobioloby.