Bio344 Molecular Biology

  Overview - The purpose of this course is to provide an in-depth analysis of the fundamental knowledge and principles upon which molecular biology is based. This will include discussions of key concepts, experiments, techniques, and even some of the scientists involved, so that a realistic feel for the area can be gleaned. Mechanisms will be emphasized, since a mechanistic framework is necessary to understand regulation and gene evolution. The main topics will be: DNA replication, recombination, repair, and transcription; RNA processing and translation; and selected topics in genomics, engineering, and HIV.

      

Instructor     Course Information and Policies

Lecture, Text & Exam  Schedule     Old Exams   Quizzes 

Molecular Biology Background

 

Lecture slides and animation:

 Introduction & History of Molecular Biology

Lec. 1 - DNA and RNA structure

Lec. 2 - DNA replication 1

        QTime Movie: DNA polymerization

        QTime Movie: Bidirectional replication

Lec. 3 - DNA replication 2

        QTime Movie: Helicase action

        QTime Movie: Pol III dimer synthesizing leading & lagging strands 

Lec. 4 - DNA replication 3 & Chromatin 1

        QTime Movie: Packing DNA into a eukaryotic nucleus

Lec. 5 - Chromatin 2 and Supercoiling

Lec. 6 - DNA Recombination 1

        QTime Movie: HJ & Branch Migration
         Flash animation of DNA Recombination via a Holliday Intermediate

Lec. 7 - DNA Recombination 2

Lec. 8 - Prokaryotic Transcription 1

Lec. 9 - Prokaryotic Transcription 2

Lec. 10 - Prokaryotic Transcription 3

Lec. 11 - Prokaryotic Transcription 4 & Organelle Transcription

Lec. 12 - Organelle Transcription 2 & Eukaryotic Transcription 1

Lec. 13 - Eukaryotic Transcription 2

Lec. 14 - Eukaryotic Transcription 3  

Lec. 15 - Eukaryotic Transcription 4

Lec. 16 - Eukaryotic Transcription 5:Chromatin Remodeling

Lec. 17 - RNA Capping and Polyaden.

Lec. 18 - RNA Splicing 1

Lec. 19 - RNA Splicing 2

Lec. 20 - RNA Splicing 3

Lec. 21 - RNA Editing  

Lec. 22 - RNAi/PTGS

Lec. 23 - Translation 1

Lec. 24 - Translation 2
Lec. 25 - Translation 3
Lec. 26 - Genomics
Lec. 27 - Transgenics 1
Lec. 28 - Transgenics 2
Lec. 29 - Transgenics 3

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Be sure to RELOAD all pages each time you visit this site. These pages will be changed frequently.

David L. Herrin, Molecular Cell and Developmental Biology, University of Texas at Austin; Email: herrin@mail.utexas.edu

Announcements

Jan. 3, 2012 - The lecture slides were updated. If you are asked to provide a username and password to access any of these files, just answer "cancel", since nothing on this site is password protected. If you have any problems, you can email me at the above address.

 

 

 

 

 

 

 


Links to other courses taught by Dr. Herrin.

Plant Molecular Biology (Bio 350M/388M)


 

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