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Lecture 1 - Introduction & History of Molecular Biology Fall 07 Lecture 2 - DNA&RNA structure Fall 07 Lecture 3 - DNA replication 1 Fall 07 QTime movies: DNA polymerization , Bidirectional replication Lecture 4 - DNA replication 2 Fall 07 QTime movies: Helicase action, Pol III dimer syn. leading & lagging QTime movie: The Replicon Lecture 5 - DNA replication 3 Fall 07 Lecture 6 - DNA replication 4 Fall 07
Lecture 7 - Chromatin Fall 07 Movie:
DNA wrapping and replication Lecture 9 DNA recombination 1 Fall 07 QT Movie: HJ&Branch Migration Flash animation of DNA Recombination via a Holliday Intermediate Lecture 10 DNA recombination 2 Fall 07 Lecture 11 Prokaryotic transcription 1 Fall 07 Lecture 12 Prokaryotic transcription 2 Fall 07 Lecture 13 Prokaryotic transcription 3 Fall 07 Lecture 14 Prokaryotic transcription 4 Fall 07 Lecture 15 Eukaryotic transcription 1 Fall 07 QTime movies: Initiation Complex, Transcription Lecture 16 Eukaryotic transcription 2 Fall 07 Lecture 17 Eukaryotic transcription 3 Fall 07
Lectures below are for the second half of the course: Lec. 18 - Overview of Post-transcriptional Processes & mRNA Capping Lec. 19 - Pre-mRNA Polyadenylation and 3' Processing
Lec.
24 - RNA Editing
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David L. Herrin, Ph.D. Jennifer Moon, Ph.D. Molecular Cell and Developmental Biology
Announcements (Fall 2007)
1 pm class: Fri., 12/14, 9 am, ESB 115 2 pm class: Tue., 12/18, 9 am, CPE 2.208
December 1 - lectures 27-30 were reloaded with the identical slides presented in class.
November 8 - the lectures indicated with a star were updated to include the slides on the handouts in class.
October 23 - The lectures for the 2nd part of the course were reformatted to correspond more closely to 50-minute lectures.
October 23 - The 2 pm class yesterday (Monday, 10/22) was cancelled because of a possible terrorist act (a.k.a., a bogus bomb threat).
Sept 20, 2007 - Check the Blackboard course documents folder for the student submitted questions file mentioned in class.
Sept. 11, 2007 - Please download the slightly revised syllabus on Blackboard. Contains minor changes to the lectures covered before Exam I.
Links to research-related topics in Herrin lab. Seminar at SUNY-Buffalo 9/2007. Seminar at CMB retreat, 9/2005 Links to other courses taught by Dr. Herrin. Plant Molecular Biology (Bio 350M/ 388M)
This site was last changed on 12/10/2007 |
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Overview - The purpose of this course is to provide an in-depth
analysis of the fundamental knowledge and principles upon which
molecular biology is based. This will include discussions of
key concepts, experiments, techniques, and even some of the scientists
involved, so that a realistic feel for the area can be gleaned.
Mechanisms will be emphasized, since a mechanistic
framework is necessary to understand regulation and
gene evolution. The main topics will be: DNA
replication, recombination, repair, and transcription; RNA processing
and translation; and selected topics in genomics, engineering,
and HIV.
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